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90 yttrium

Yttrium-90 Microspheres Overview. 90 Y is the radioactive element most commonly used for radioembolization. It is a pure β-emitter with a half-life of 64.2 hours, and it decays into the stable element zirconium-90. Tissue penetration of the emissions ranges from 2.5 to 11 mm Yttrium-90 is used in nuclear medicine. Since yttrium-90 is a synthetic isotope and has circumscribed uses, releases to the environment of yttrium-90 would be very limited. Exposure to yttrium-90 would be limited to individuals involved in the research or production of yttrium-90, or to individuals receiving or administering treatment using

Yttrium 90 - an overview ScienceDirect Topic

  1. Yttrium-90 (90 Y) is a radioisotope; derived from the decay of 90 Sr.Yttrium-90 decays due to the emission of β- particles, with a half-life of 2.67 days. It can be used for metabolic radiopharmaceutical therapy, for example: non-Hodgkin's B-cell lymphomas radioimmunotherapy (radiopharmaceutical therapy and immunotherapy)
  2. Yttrium-90 er et forfallsprodukt av strontium-90 som utgjør omtrent 5% av de isotopiske datterisotoper når uran klyves. Yttrium-90 produseres ved kjemisk separasjon med høy renhet fra strontium-90, et klyvingsprodukt av uran i kjernereaktorer. Medisinsk søknad
  3. Yttrium 90 is produced either by the neutron irradiation of stable yttrium, or by chemical separation from its parent isotope, strontium 90. Production from stable yttrium is rather expensive, and the specific activity of the product is necessarily limited, but this isotope may be produced carrier-free for thera

Yttrium-90 Y - PubChe

A radioconjugate consisting of the octreotide derivative edotreotide labeled with yttrium 90 (Y-90) with potential radiotherapeutic uses. Similar to octreotide, yttrium Y 90-edotreotide binds to somatostatin receptors (SSTRs), especially type 2 receptors, present on the cell membranes of many types of neuroendocrine tumor cells, delivering tissue-specific, beta-emitting nuclide Y-90-mediated. Yttrium-90 Radioembolization By Arkadiy Kheyfits Radiology Today Vol. 11 No. 9 P. 20. This new path in liver cancer treatment is becoming more widely traveled. Nonresectable primary and metastatic liver cancers carried a bleak prognosis with limited treatment options—until recently Yttrium er et grunnstoff med kjemisk symbol Y og atomnummer 39. Grunnstoffet er et sølvaktig transisjonsmetall, med kjemiske fellestrekk med lantanoidene, og blir ofte klassifisert som en sjelden jordart. Nesten alle funn av yttrium er gjort i kombinasjon med funn av mineraler som inneholder sjeldne jordarter, og yttrium er aldri funnet naturlig i fri tilstand Yttrium er et metall med utseende som sølv. Rent er det lett å bearbeide, men små mengder oksygen løst i metallet øker hardheten.Yttrium er det andre grunnstoffet i gruppe 3 i periodesystemet. I sine kjemiske forbindelser er yttrium treverdig.89Y er den eneste stabile isotopen av yttrium. General handling precautions for Yttrium-90 1. Designate area for handling 90Y and clearly label all containers. 2. Store 90Y behind lead shielding. 3. Wear extremity and whole body dosimeters while han-dling mCi (37 MBq) quantities. 4. Handle millicurie (37 MBq) quantities of 90Y behind 1.3-cm (0.5-in) thick Lucite® shielding. Where necessary

Yttrium isotopes are among the most common products of the nuclear fission of uranium in nuclear explosions and nuclear reactors. In the context of nuclear waste management, the most important isotopes of yttrium are 91 Y and 90 Y, with half-lives of 58.51 days and 64 hours, respectively Yttrium-90 production. We are involved in the production of medical isotopes for medical devices used in radioembolization for a long time. Bot yttrium-90 and holmium-166 are part of NRG's product portfolio. Our full-service approach includes preparing irradiation capsules, irradiation, waste handling and logistics Yttrium [ˈʏtri̯ʊm] ist ein chemisches Element mit dem Elementsymbol Y und der Ordnungszahl 39. Es zählt zu den Übergangsmetallen sowie den Seltenerdmetallen, im Periodensystem steht es in der 5. Periode sowie der 3. Nebengruppe, bzw. der 3. IUPAC-Gruppe oder Scandiumgruppe.Yttrium ist nach dem ersten Fundort, der Grube Ytterby bei Stockholm, benannt, wie auch Ytterbium, Terbium und Erbiu Yttrium Y-90 cation. Yttrium Y 90 tacatuzumab. UNII-D0U4XMW54Z. AFP-Cide. Yttrium Y 90 tacatuzumab [USAN] Yttrium, isotope of mass 90 (90Y3+) hAFP-31. D0U4XMW54Z. 500784-58-7. 880649-77-4. Immunoglobulin G1, anti-(human alpha-fetoprotein) (human-mouse monoclonal hAFP-31 gamma 1-chain), disulfide with human-mouse monoclonal hAFP-31 kappa-chain.

Yttrium er 7 bokstaver langt og inneholder 3 vokaler og 4 konsonanter. For info som ikke er relatert til kryssord, så kan du slå opp yttrium i ordboka Yttrium is found in the rare-earth mineral monazite, of which it makes 2.5%, and in smaller quantities in other minerals such as barnasite, fergusonite and smarskite. The output of yttrium is about 600 tonnes per year, measured as yttrium oxide, and world reserves are estimated to be around 9 million tonnes. Health effects of yttrium Natural yttrium (39 Y) is composed of a single isotope yttrium-89.The most stable radioisotopes are 88 Y, which has a half-life of 106.6 days and 91 Y with a half-life of 58.51 days. All the other isotopes have half-lives of less than a day, except 87 Y, which has a half-life of 79.8 hours, and 90 Y, with 64 hours. The dominant decay mode below the stable 89 Y is electron capture and the.

Yttrium-90 Radiology Reference Article Radiopaedia

Yttrium-90 is a reactor-produced isotope with a half-life of 64.1 hours used in the radiation therapy. Discover our Y-90 product portfolio below Yttrium (Y), chemical element, a rare-earth metal of Group 3 of the periodic table. Yttrium is a silvery white, moderately soft, ductile metal. It is quite stable in air; rapid oxidation begins above approximately 450 °C (840 °F), resulting in Y2O3. The metal readily reacts with dilute yttrium-90: ( it'rē-ŭm ), An artificial radioactive isotope with a physical half-life of 2.67 days, which decays with the emission of a 2.282 MeV β particle; used as an implant in pituitary ablation What does the equipment look like? X-ray equipment, a catheter and microspheres, or tiny glass beads filled with the radioisotope yttrium-90 are used in this procedure.. Radioembolization procedures are typically performed using x-ray guidance. The equipment typically used for this examination consists of a radiographic table, one or two x-ray tubes and a television-like monitor that is.

Yttrium-90 - Yttrium-90 - qwe

Yttrium er et sølvfarget, metallisk skinnenede transisjonsmetall som er relativt stabilt i luft. Når det belyses kan det få et rosa skjær. Det regnes for å være giftig og kan føre til lungelidelser hos mennesker. Yttrium har mange bruksområder; Det viktigste er i fremstillingen av lysstoff som brukes blant annet i LED-lys og i skjermer Y-90 radioembolization is a procedure that delivers radiation therapy directly to the tumors in the liver. With the help of imaging guidance, an interventional radiologist makes a small incision and guides a tiny tube (called a catheter) into the artery that supplies blood to the liver The Yttrium-90 radiates from within and it can be viewed as 'internal' radiation. Radio-embolization is a palliative, not a curative, treatment. However, patients benefit by extending their lives and improving their quality of life. It is performed as an outpatient treatment Strontium har fått navnet sitt fra mineralet strontianitt som igjen er oppkalt etter landsbyen Strontian på den skotske vestkysten. Det var i blygruvene her at mineralet ble funnet første gang i 1787. I 1790 la den irske kjemikeren Adair Crawford merke til at mineralet var annerledes enn andre bariummineraler

Radioactive Yttrium 90: A review of its properties

This video is about the radioisotope Yttrium-90 and how it's used in medicine to treat liver tumours. I'll also explore the advantages and disadvantages of Yttrium-90 radiotherapy and justify its. The Yttrium-90 irradiates from within and can be viewed as internal radiation or brachytherapy. Radioembolization is a palliative, not a curative, treatment. Patients may benefit by extending their lives and improving their quality of life The addition of yttrium-90 ((90) Y)-ibritumomab tiuxetan (Zevalin(®)) to BEAM (Z-BEAM) is increasingly being used to improve outcomes and overcome refractory disease. We conducted a literature review and meta-analysis in order to evaluate the clinical effects of Z-BEAM followed by ASCT in patients with DLBCL Yttrium-90 microspheres are radioactive particles which are increasingly being employed for treating patients with unresectable hepatocellular carcinoma (HCC). The procedure is called radioembolization. It involves the injection of micron-sized embolic particles loaded with a radioisotope by use of

Definition of yttrium Y 90-edotreotide - NCI Drug

90 Yttrium is a decay product of 90 Strontium with a half-life of 64.1 hours. It decays by emission of beta radiation of 2.281 MeV (100%) of maximal energy to 90 Zirconium. 90 Yttrium chloride solution is available with the activity ranging from 0.1 - 50 GBq per vial at reference time and a volume from 0.1 - 5ml per vial as requested. It is delivered in a 3 ml V or 10 ml flat bottom glass. In medicine, yttrium 90 is used to help kill cancer cells. Y-90 can be attached to antibodies to target cancer cells directly or it can be used in radioactive beads, which travel to the tumor site. Yttrium (90Y) CAS registry number (Chemical Abstracts Service) 0010098-91-6. Therapeutic Category. Antineoplastic agent: Radioactive isotope. Chemical Names. Yttrium (⁹⁰Y), colloidal. Yttrium (⁹⁰Y), isotope of maβ 90. Foreign Names. Yttrium (⁹⁰Y) kolloidal (German) Yttrium-90 (French) Itrio-90 (Spanish) Generic Names. Yttrium. The radioactive isotope yttrium-90 is used in radiation therapy to treat liver cancer and some other cancers. Current research Subramanian said that yttrium was easier to work with and less. 7. Murthy R, Nunez R, Szklaruk J, et al. Yttrium-90 microsphere therapy for hepatic malignancy: devices, indications, technical considerations, and potential complications. Radiographics. 2005;25(suppl 1):S41-55. 8. Fischman AM, Swinburne NC, Patel RS. A technical guide describing the use of transradial access technique for endovascular.

Yttrium aluminium garnet, also known as YAG, is a very important synthetic mineral. It is used to make hard, artificial diamonds, which sparkle just like the real ones. What is more, by introducing small quantities of lanthanide ions, materials with a range of useful properties can be made YTTRIUM Y-90 1K8M7UR6O1 Overview Structure Names 6: Classification 1: Identifiers 5: Relationships 1: Active Moiety 1: Notes 1: Audit Info References 13: Moieties 1: Substance Class: Chemical Record UNII: 1K8M7UR6O1. Record Status: Validated: Record Version: Show Definitional References Hide Definitional References.

Yttrium-90 Radioembolization - Radiology Today Magazin

In a pilot study, DOTA-d-Phe1-Tyr3-octreotide (DOTATOC), which can be labelled with the β-emitting radioisotope yttrium-90, has recently been used for the treatment of patients with advanced somatostatin receptor-positive tumours who had no other treatment option. The aim of the present study was to elucidate the therapeutic potential of 90Y-DOTATOC in a larger number of patients employing a. Yttrium-90 (90 Y, T1/2 64.14 h) is a key example of a high beta energy-emitting radionuclide which is available from the strontium-90 (90 Sr)/ 90 Y radionuclide generator system.Clinical uses of 90 Y-labeled radiopharmaceutical agents have been pursued for many years and many applications have proven to be clinical effective. These most notably include the application of 90 Y-labeled.

Name: Yttrium: Symbol: Y: Atomic Number: 39: Atomic Mass: 88.90585 atomic mass units: Number of Protons: 39: Number of Neutrons: 50: Number of Electrons: 39: Melting. Des aiguilles en yttrium-90, qui peuvent couper de manière plus précises que des scalpels, ont été utilisées pour agir sur les nerfs qui transmettent la douleur dans la moelle épinière [12], et l'yttrium 90-est également utilisé pour pratiquer des synoviorthèses isotopiques dans le traitement d'inflammations articulaires, particulièrement des genoux, pour des patients atteints par. This page is based on the copyrighted Wikipedia article Yttrium-90 (); it is used under the Creative Commons Attribution-ShareAlike 3.0 Unported License.You may redistribute it, verbatim or modified, providing that you comply with the terms of the CC-BY-SA Kemiske egenskaber. Yttrium har kemiske egenskaber der minder om lanthanidernes: Sammenhængende klumper af yttrium er relativt modstandsdygtigt overfor atmosfærisk luft, mens yttrium i spåner kan antændes ved temperaturer over 400 °C, og yttrium i form af findelt pulver er ustabilt i luft ved stuetemperatur.. I kemiske forbindelser optræder yttrium med oxidationstallet +3

Yttrium - Wikipedi

Yttrium iron garnets are used to filter microwaves and as transmitters and transducers of acoustic energy. Yttrium aluminum garnets, with a hardness of 8.5, are used to simulate diamond gemstones. Small quantities of yttrium may be added to reduce the grain size in chromium, molybdenum, zirconium, and titanium, and to increase the strength of aluminum and magnesium alloys Yttrium (lat. yttrium) on maametalleihin kuuluva metallimainen alkuaine. Se on jaksollisessa järjestelmässä 39. alkuaine.Sen tiheys huoneenlämmössä on 4,47×10³ kg/m³. Sen sulamispiste on 1 796 K, kemiallinen merkki Y ja atomipaino 88,91. Alkuaineen löysi suomalainen kemisti Johan Gadolin 1794. Yttrium on nimetty ruotsalaisen kylän Ytterbyn mukaan Whenever yttrium is sliced into shavings or small particles, it actually becomes unstable. In the solar system, yttrium was created from stellar nucleosynthesis. Isotopes of yttrium are some of the most common by-products of nuclear fission. Two of yttrium's isotopes, Y-90 and Y-91, are vital in nuclear waste management Yttrium-90. Important: The information below refers to products available in the United States that contain yttrium-90 Search results for yttrium oxide at Sigma-Aldrich. Compare Products: Select up to 4 products. *Please select more than one item to compar

4 Targeted Radionuclide Therapy | Advancing Nuclear

Yttrium-90 ibritumomab tiuxetan in the treatment of non-Hodgkin lymphoma Matthew S McKinney, Anne W Beaven Division of Hematologic Malignancies, Department of Medicine, Duke University Medical Center, Durham, NC, USA Abstract: Most cases of indolent non-Hodgkin lymphoma (NHL) are incurable with standard chemoimmunotherapy approaches, and patients with relapsed/refractory disease have. Yttrium-90 microspheres, when given, will preferentially flow to the tumour because of the increased Arterial Vascular supply. The diameter of SIR-Spheres enables them to become implanted in the tumour microvasculature, but they are too large to pass through the end arterioles into the hepatic sinusoids, which have a restrictive diameter of 8-10 micro Yttriga | The sterile [Y-90]Yttrium chloride solution is registered as a medicinal product in the EU and submitted to the US FDA as a Type II DMF OSTI.GOV Journal Article: Yttrium-90 citrate colloid for radioisotope synovectom

yttrium - Store norske leksiko

Best Patrons: Stan Presolski, reinforcedconcrete, Dean Bailey, Bob Drucker, Pradeep Sekar, Applied Science, Purple Pill, afreeflyingsoul, Alfred Barnat, Saba.. Search results for yttrium at Sigma-Aldrich. Compare Products: Select up to 4 products. *Please select more than one item to compar

90 Zr: γ - 91 Y syn: 58.5 d β − 91 Zr: γ references: Yttrium is a chemical element wi seembol Y an atomic nummer 39. It is a sillery-metallic transeetion metal chemically seemilar tae the lanthanides an it haes eften been clessifee'd as a rare yird element Yttrium-90 of 90 Y is een onstabiele radioactieve isotoop van yttrium, een overgangsmetaal.De isotoop komt van nature niet op Aarde voor.. Yttrium-90 ontstaat onder meer bij het radioactief verval van strontium-90.. Radioactief verval. Yttrium-90 vervalt door β −-verval tot de stabiele isotoop zirkonium-90: + − + ¯ De halveringstijd bedraagt 2,66 dagen Yttrium is used as a catalyst in ethylene polymerization. Yttrium-90, a radioactive isotope, is used in treatments for various cancers and is used in precision medical needles to sever pain-transmitting nerves in the spinal cord. Yttrium oxide is the most important compound of yttrium Strontium-90 A fission product with properties close to calcium. Strontium-90 is with cesium-137 a major radioactive product of nuclear fission. After the explosion of an atomic bomb or within a nuclear reactor, it is abundant: 5.8% of uranium-235 fissions produces this radioelement

90 pm (ladning: +3) van der Waals radius Yttrium vert brukt i legeringar med andre metall. Stoffet vert brukt som katalysator. Bakgrunnsstoff. Webelements - yttrium. Denne kjemiartikkelen er ei spire. Du kan hjelpe Nynorsk Wikipedia gjennom å Denne sida vart sist endra den 2. Yttrium is a monoisotopic element and its atomic weight is determined solely by its isotope 89 Y. The Commission last revised the standard atomic weight of yttrium in 2017 based on the latest Atomic Mass Evaluation by IUPAP Yttrium-90 decays by emission of beta particles, with a physical half-life of 64.1 hours and a decay energy of 2.28 MeV. Effects in breastfed infants. Yttrium-90 decays by emission of beta particles, with a physical half-life of 64.1 hours and a decay energy of 2.28 MeV. Possible effects on lactatio Radioimmunotherapy (RIT) after an induction phase with conventional chemoimmunotherapy became an attractive strategy of consolidation for patients with advanced follicular lymphoma: in particular, in many studies RIT was represented by yttrium‐90‐ibritumomab tiuxetan (90 Y‐ IT).Independently by the different front‐line treatment, updates on the long‐term follow‐up of these studies. yttrium-90 definition: Noun (uncountable) 1. (physics) An isotope of yttrium, 9039Y, that is used in radiotherapy..

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Yttrium-90 - Advancing Nuclear Medicin

イットリウム(ラテン語: yttrium 英語発音: [ˈɪtriəm] )は原子番号39の元素である。 元素記号はYである。単体は軟らかく銀光沢をもつ金属である。 遷移金属に属すがランタノイドと化学的性質が似ているので希土類元素に分類される 。 唯一の安定同位体 89 Yのみ希土類鉱物中に存在する Name: Yttrium Symbol: Y Atomic Number: 39 Atomic Mass: 88.90585 amu Melting Point: 1523.0 °C (1796.15 K, 2773.4 °F) Boiling Point: 3337.0 °C (3610.15 K, 6038.6 °F) Number of Protons/Electrons: 39 Number of Neutrons: 50 Classification: Transition Metal Crystal Structure: Hexagonal Density @ 293 K: 4.469 g/cm 3 Color: silvery Atomic Structur Yttrium was discovered by Johan Gadolin, a Finnish chemist, while analyzing the composition of the mineral gadolinite ((Ce, La, Nd, Y) 2 FeBe 2 Si 2 O 10) in 1789.Gadolinite, which was named for Johan Gadolin, was discovered several years earlier in a quarry near the town of Ytterby, Sweden STRONTIUM 90 + YTTRIUM 90 FICHE RADIONUCLEIDE 38 90Sr . 2 1ère édition : 01/08/2001 90Sr - Emissions par les installations nucléaires La deuxième source de 90Sr dans l'environnement est le cycle du combustible. Du 90Sr est créé par fission au sein des réacteurs Yttrium-90 is a minimally invasive treatment. In collaboration with interventional Radiology the use of intra-arterial Yttrium,-90 microspheres is used to treat liver tumors. This procedure often controls and or shrinks tumors

Yttrium Y 90 tacatuzumab Y+3 - PubChe

In recent years, transarterial radioembolization (TARE) with Yttrium-90 (Y90) has emerged as a technique for treating malignant neoplasms in the liver. Compared with other locoregional therapies, such as transarterial chemoembolization (TACE), patients who underwent TARE with Y90 have higher tumor response rates and better outcomes Yttrium-90 microsphere radioembolization, is a non-surgical procedure to treat inoperable liver cancer and liver metastases. Also known as selective internal radiation therapy (SIRT) treats lesions in the liver from other cancers in patients who cannot have the tumors surgically removed 90 YTTRIUM PERIODIC TABLE, PERIODIC YTTRIUM TABLE Ditulis admob11 Minggu, 22 Februari 2015 Tulis Komentar Edit *** 980 yttrium periodic table 989 ** Product [90Y]Yttrium Chloride solution Half-life 64.1 hours Decay energy E max = 2.28 MeV; 100 % -Chemical form [90Y]YCI 3 in 0.04 M HCI solution Concentration 1 GBq/ml Specific activity Product is carrier free Activity 0.1 - 50 GBq per vial at reference time as requested Bulk material Various concentrations availabl An artificial radioactive isotope with a physical half life of 2.67 days, which decays with the emission of a 2.282 MeV β particle; used as an implant in pituitary ablation. * * * n. an artificial radioactive isotope of the element yttrium, use

Find patient medical information for Kit For Yttrium-90-Ibritumomab Intravenous on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings Yttrium-90 may be obtained by neutron irradiation of yttrium-89 or from strontium-90, a product of uranium fission. Production of radiopharmaceutical preparation. Yttrium-90 is bound to silicate to form a fine colloid. Yttrium (90 Y) silicate injection may have the pH adjusted and may contain. Isotopes of strontium-89 and yttrium-90 are finding more and more application for the purposes of nuclear medicine thanks to their properties such as a short half-life period (Т 1/2 89 Sr = 53,6 days, T 1/2 90 Y = 64,3 hours), high energy of beta-particles, absence of gamma-quanta, possibility to obtain isotopes of high specific activity without carrier Yttrium (Y) 90 Radioactive Isotope Decay Calculator. Online radioactive decay calculator that allows you to find out the radioactivity decay in Yttrium (Y) 90. Note: The calculation of radioactivity in minerals is based on certain assumptions

Radioembolization with Yttrium 90

Yttrium-90 obtained from 90 Sr/ 90 Y generator is no carrier added (NCA) and hence very high specific activity 90 Y tracers could be prepared which might be more efficacious for therapy [245] yttrium-90. yttrium-90: translation. An artificial radioactive isotope with a physical.

YTTRIUM Y-90 LABETUZUMAB 1N0454DEUM Overview Names 5: Classification 2: Identifiers 3: Subunits 4: Disulfide Links 16: Relationships 3: Active Moiety 2: Modifications 1: Characteristic Attributes 1: Notes 2: Audit Info References 13: Substance Class: Protein. 90 Y is produced by bombardment of yttrium 89 with neutrons in a nuclear reactor. It has a physical half-life of 64.2 hours (2.67 days), and it decays to stable zirconium 90. 90 Y emits pure high-energy beta rays (energy maximum, 2.27 MeV; mean, 0.9367 MeV) with an average penetration range of 2.5 mm and a maximum range of 11 mm in tissue A radioimmunotherapeutic agent consisting of a murine monoclonal anti-CD20 antibody (ibritumomab) linked by the chelator tiuxetan to the radioisotope yttrium-90 (Y 90). Yttrium Y 90 ibritumomab tiuxetan binds to and specifically delivers beta radiation to CD20-expressing tumor cells, thereby minimizing the systemic effects of radiation Yttrium-90, 90Y, is a medically significant isotope of yttrium. Yttrium-90 has a wide and valuable use in radiation therapy to treat cancer

FIS - Radioembolization - YouTubeMetallrohstoffe: Metallrohstoffe im Alltag - WerkstoffeThe Most Gangsta Yearbook Quote to Ever Exist | Complex

90 Y, one of the isotopes of yttrium, exists in equilibrium with its parent 90 Sr, a product of nuclear explosions. Yttrium has been considered for use as a nodulizer for producing nodular cast iron, in which the graphite forms compact nodules instead of the usual flakes. Such iron has increased ductility Is a radioactive isotope used in the treatment of NETs Yttrium-90: | | | |Yttrium-90| | ||Full table|| | World Heritage Encyclopedia, the aggregation of the largest online encyclopedias available, and the most. Yttrium-90 is used in the treatment of hepatocellular carcinoma (HCC) and inoperable colorectal metastasis to the liver by radioembolization. 1 It has also been researched in treating pancreatic, lung, breast and cervical hepatic metastasis but those studies were with small populations. 1 Y 90 almost exclusively emits beta minus radiation, with an average energy of 926.7 keV, to a maximum. The administration of 0-2-0-4 mCi 90 yttrium (90Y) into a normal rabbit knee joint fails to induce medical synovectomy and results in the proliferation of the synovialis. The synovial mesothelium shows early radiation damage but subsequently follows a restitution of the whole. Later (within 4 to 16 weeks) an extensive fibrosis of the stratum synovialis develops, as well as an occlusion and.

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